1,8-Dioxo-Decahydroacridines Synthesis Using a Maghnite-H+ Clay as Acid Eco-Friendly Catalyst

Abstract

A simple and efficient approach for the synthesis of 1,8-dioxo-decahydroacridines 4a-f was proposed by multicomponent one-pot condensation of an aromatic aldehyde, 1,3-diketones and ammonium acetate in the presence of Maghnite-H+, an Algerian proton-exchange montmorillonite clay, as a green catalyst. Maghnite-H+ is an efficient, economical, recyclable and environmentally friendly catalyst. Its catalytic effect is considerable for the condensation reaction, with good to excellent yields in a short time.